Inhibition of Extracellular Cyclophilins with Cyclosporine Analogue and Development of Atherosclerosis in Apolipoprotein E Deficient Mice
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چکیده
منابع مشابه
Inhibition of extracellular cyclophilins with cyclosporine analog and development of atherosclerosis in apolipoprotein E-deficient mice.
Cyclophilins exert both intracellular and extracellular activities related to immune responses and inflammation, which have been implicated in pathogenesis of atherosclerosis. Pan-inhibition of cyclophilins has both pro- and antiatherosclerotic properties, but specific contributions of extracellular and intracellular cyclophilins to these effects have not been characterized. Here, using selecti...
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تاریخ انتشار 2015